摘要
3-(α-甲氧基)甲烯基苯并呋喃-2(3H)-酮的合成是合成嘧菌酯中最关键的一步。本文重点研究了由邻羟基苯乙酸合成3-(α-甲氧基)甲烯基苯并呋喃-2(3H)-酮的反应及后处理操作,缩短了反应时间,简化了后处理程序。与文献相比,反应收率提高了30%多,并且方法简单,步骤少,成本低,在工业上易于实现。
The synthesis of 3-(α-methoxy)methylenebezofuran-2(3H)-ketone was the most important step in the synthesis of azoxystrobin.In this paper,the synthesis of 3-(α-methoxy)methylenebezofuran-2(3H)-ketone from o-hydroxyphenylacetic acid and its post-treatment were studied.The reaction time was shortened and the post-processing procedure was reduced.Compared with the literature,the yield of the reaction was increased by more than 30%,and the method was simple,the steps were few,the cost was low,and it was easy to realize in industry.
作者
许标
XU Biao(Hunan Food and Drug Vocational College,Changsha 410208,China)
出处
《化工技术与开发》
CAS
2018年第11期10-11,共2页
Technology & Development of Chemical Industry
关键词
合成工艺
甲烯基苯并呋喃-酮
后处理
synthesis technology
methylenebezofuran-ketone
post-treatment
