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Determination of 50% endpoint titer using a simple formula 被引量:13

Determination of 50% endpoint titer using a simple formula
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摘要 Two commonly used methods for calculating 50% endpoint using serial dilutions are Spearman-Karber method and Reed and Muench method. To understand/apply the above formulas, moderate statistical/mathematical skills are necessary. In this paper, a simple formula/method for calculating 50% endpoints has been proposed. The formula yields essentially similar results as those of the SpearmanKarber method. The formula has been rigorously evaluated with several samples. Two commonly used methods for calculating 50% endpoint using serial dilutions are Spearman-Karber method and Reed and Muench method. To understand/apply the above formulas, moderate statistical/mathematical skills are necessary. In this paper, a simple formula/method for calculating 50% endpoints has been proposed. The formula yields essentially similar results as those of the SpearmanKarber method. The formula has been rigorously evaluated with several samples.
机构地区 Division of Virology
出处 《World Journal of Virology》 2016年第2期85-86,共2页 世界病毒学杂志
关键词 ENDPOINT DILUTION TCID50 Spearman-Karber REED and Muench Endpoint dilution TCID50 Spearman-Karber Reed and Muench
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