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Renal cell carcinoma: Evolving and emerging subtypes 被引量:7

Renal cell carcinoma: Evolving and emerging subtypes
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摘要 Our knowledge of renal cell carcinoma(RCC) is rapidly expanding. For those who diagnose and treat RCC, it is important to understand the new developments. In recent years, many new renal tumors have been described and defined, and our understanding of the biology and clinical correlates of these tumors is changing. Evolving concepts in Xp11 translocation carcinoma, mucinous tubular and spindle cell carcinoma, multilocular cystic clear cell RCC, and carcinoma associated with neuroblastoma are addressed within this review. Tubulocystic carcinoma, thyroid-like follicular carcinoma of kidney, acquired cystic disease-associated RCC, and clear cell papillary RCC are also described. Finally, candidate entities, including RCC with t(6;11) translocation, hybrid oncocytoma/chromophobe RCC, hereditary leiomyomatosis and RCC syndrome, and renal angiomyoadenomatous tumor are reviewed. Knowledge of these new entities is important for diagnosis, treatment and subsequent prognosis. This review provides a targeted summary of new developments in RCC. Our knowledge of renal cell carcinoma(RCC) is rapidly expanding. For those who diagnose and treat RCC, it is important to understand the new developments. In recent years, many new renal tumors have been described and defined, and our understanding of the biology and clinical correlates of these tumors is changing. Evolving concepts in Xp11 translocation carcinoma, mucinous tubular and spindle cell carcinoma, multilocular cystic clear cell RCC, and carcinoma associated with neuroblastoma are addressed within this review. Tubulocystic carcinoma, thyroid-like follicular carcinoma of kidney, acquired cystic disease-associated RCC, and clear cell papillary RCC are also described. Finally, candidate entities, including RCC with t(6;11) translocation, hybrid oncocytoma/chromophobe RCC, hereditary leiomyomatosis and RCC syndrome, and renal angiomyoadenomatous tumor are reviewed. Knowledge of these new entities is important for diagnosis, treatment and subsequent prognosis. This review provides a targeted summary of new developments in RCC.
出处 《World Journal of Clinical Cases》 SCIE 2013年第9期262-275,共14页 世界临床病例杂志
关键词 RENAL CELL CARCINOMA SUBTYPES Xp11 TRANSLOCATION Mucinous tubular and spindle CELL Multilocular CYSTIC clear CELL CARCINOMA associated with neuroblastoma recently described entities Clear CELL papillary RENAL CELL CARCINOMA Acquired CYSTIC kidney disease Hereditary leiomyomatosis Candidate entities RENAL CELL CARCINOMA with t(6 11)translocation Renal cell carcinoma Subtypes Xp11 translocation Mucinous tubular and spindle cell Multilocular cystic clear cell Carcinoma associated with neuroblastoma recently described entities Clear cell papillary renal cell carcinoma Acquired cystic kidney disease Hereditary leiomyomatosis Candidate entities Renal cell carcinoma witht(6 11) translocation
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