镍钛机用器械联合超声冲洗对慢性根尖周炎根管内毒素的清除效果

Clearup Effects of Nickel-titanium Rotary Instrument and Ultrasonic Irrigation on Endotoxin Level in Root Canals of Chronic Apical Periodontitis

目的:研究镍钛机用器械联合超声冲洗对慢性根尖周炎患牙根管内毒素的清除效果。方法:临床选择上颌前牙慢性根尖周炎30例,随机分为3组,A组镍钛机用器械预备常规冲洗,B组镍钛机用器械预备后无菌蒸馏水超声冲洗1min,C组镍钛机用器械预备后3%次氯酸钠溶液超声冲洗1min,检测患牙机械预备、超声冲洗后根管内毒素的含量变化。结果:3组患牙治疗前内毒素含量的差异无统计学意义(P>0.05);A、B、C三组治疗后内毒素含量分别为(8.52±2.04)EU/mL,(1.61±0.41)EU/mL,(0.22±0.11)EU/mL,差异有统计学意义(P<0.05)。结论:镍钛机用器械联合超声冲洗对根管内毒素有良好的清除作用;镍钛机用器械预备后以3%次氯酸钠溶液超声冲洗1min对根管内毒素的清除效果优于无菌蒸馏水超声冲洗1min。

Objective:To study the clearup effects of nickel-titanium rotary instrument and ultrasonic irrigation on the endotoxin level in root canals of chronic apical periodontitis.Methods:Thirty maxillary anterior teeth clinically diagnosed with chronic apical periodontitis were randomized into three groups.Group A was prepared with nickel-titanium rotary instrument.Group B was given one minute ultrasonic irrigation with sterile distilled water after root canal preparation with nickel-titanium rotary instrument.Group C was given one minute ultrasonic irrigation with 3%NaClO after root canal preparation with nickel-titanium rotary instrument.The concentration of endotoxin in the root canals was detected before and after treatments.Results:There were no statistical differences between three groups before treatments(P>0.05).The endotoxin concentrations in the three groups were(8.52±2.04)EU/mL,(1.61±0.41)EU/mL,and(0.22±0.11)EU/mL,respectively after treatments(P<0.05).Conclusion:Nickel-titanium rotary instrument and ultrasonic irrigation has a good effect on the clearup effect of endotoxin level in the root canals,and the effect with ultrasonic irrigation for one minute with 3%NaClO was better than ultrasonic irrigation for one minute with sterile distilled water.