摘要
Periodontitis is known to be a risk factor for abdominal aortic aneurysm(AAA). However, the influence of periodontitis on AAA development is to be elucidated. This article is to review the relationship between periodontitis and AAA. We focused on the roles of specific periodontopathic bacteria in AAA, matrix metalloproteinases and toll-like receptors in the pathophysiology in the section of experimental analysis. Furthermore, we showed clinical data of periodontitis in patients with AAA. We concluded that periodontal pathogens play a critical role in the AAA development.
Periodontitis is known to be a risk factor for abdominal aortic aneurysm(AAA). However, the influence of periodontitis on AAA development is to be elucidated. This article is to review the relationship between periodontitis and AAA. We focused on the roles of specific periodontopathic bacteria in AAA, matrix metalloproteinases and toll-like receptors in the pathophysiology in the section of experimental analysis. Furthermore, we showed clinical data of periodontitis in patients with AAA. We concluded that periodontal pathogens play a critical role in the AAA development.
基金
Supported by Mitsui Life Social Welfare Foundation
Daiwa Security Health Foundation
Mitsui Sumitomo Marine Welfare Foundation
Institute of Geriatric Dentistry Foundation
Institute of St.Luka Life Science Foundation
Health Welfare Foundation
Taiyo Life Welfare Foundation
the 8020 Foundation
Terumo Science Foundation
Pfizer Health Research Foundation
General Health Promotion Foundation
