日常饮茶与视网膜血管管径的相关性

Association between Daily Tea Consumption and Retinal Vascular Caliber

目的:探讨日常饮茶种类和饮茶量与视网膜血管管径的相关关系。方法:横断面研究。纳入年龄40岁及以上、无严重心脑血管疾患的广州市公务员4430人。通过问卷采集参与者日常主要饮茶种类(包括绿茶、乌龙茶、红茶或普洱茶3类)和平均饮茶量(分为从不饮茶、偶有饮茶、少于每天1杯、每天1~2杯、每天2杯以上5组)。通过IVAN眼底血管分析系统测定研究对象的眼底照片评估视网膜血管管径。多重线性回归模型分析日常饮茶与视网膜血管管径的相关关系。结果:本研究参与者年龄为(58.8±9.9)岁,其中男性占56.00%,从不饮茶为775人(17.49%),饮用绿茶、乌龙茶、红茶的人数分别是645人(14.56%)、1240人(27.99%)、1770人(39.95%)。在矫正了年龄、血压等传统心脑血管危险因素及日常生活习惯后,在3个不同的饮茶种类人群中,视网膜血管管径与饮茶量不相关(P>0.05)。结论:日常生活的饮茶量与视网膜血管管径并无相关关系。

Objective:To assess the association between daily tea consumption and retinal vascular caliber in Chinese people.Methods:In this cross-sectional study,4 430 subjects aged 40 years or older without a history of cardiovascular events were enrolled.Standard retinal photos and a validated computer-based program were used to measure retinal vascular caliber.A self-report questionnaire was administrated to obtain data regarding tea consumption and other socio-demographic information.Daily tea consumption was quantified into five dose categories(never,occasionally,<1 cup/day,1-2 cups/day and>2 cups/day)and three common tea types(green,oolong and black/Pu'er tea,according to the degree of fermentation).Multivariate linear regression models were adopted to assess the cross-sectional association of tea consumption with retinal vascular caliber.Results:The age of the study participants was 58.8±9.9 years.Among them,775(17.49%)never consumed tea and,645(14.56%),1 240(27.99%)and 1 770(39.95%)were accustomed to green,oolong and black/Pu'er tea,respectively.Retinal vascular calibers were not associated with doses of tea consumption after adjusting for lifestyle factors and other cardiovascular confounders,whether analyzed in all participants or in subpopulations accustomed to distinct tea types(all P>0.05).Conclusions:There is no significant association between daily tea consumption and retinal vascular caliber in a Chinese population.