摘要
糖尿病视网膜病变(diabetic retinopathy,DR)是糖尿病的一种威胁视力的并发症,是致盲的主要原因。DR发病机制复杂,目前尚不明确。大量的证据使人们意识到DR不仅是一种血管疾病,而且是一种神经退行性疾病。目前针对DR治疗方案效果有限,DR的早期诊断、防治至关重要。本文就近两年DR的诊断、治疗的最新研究进展及新的治疗靶点进行综述。
Diabetic retinopathy(DR)is a sight-threatening complication of diabetes and the leading cause of vision loss.The pathogenesis of DR is complex and not clear.DR traditionally has been considered as a microvascular disease;however,new evidence suggests that it is also a neurodegenerative disease.The effectiveness of current treatments for DR is limited.Therefore,a multidisciplinary approach and novel strategies to detect,prevent and treat DR in the early stages are needed.This review provides an update on the novel developments in DR diagnosis,treatment and new therapeutic targets in the nearly two years.
作者
张佳慧
陈晓隆
ZHANG Jia-Hui;CHEN Xiao-Long(Department of Ophthalmology,Shengjing Hospital of China Medical University,Shenyang 110001,Liaoning Province,China)
出处
《眼科新进展》
CAS
北大核心
2018年第12期1185-1190,共6页
Recent Advances in Ophthalmology
关键词
糖尿病视网膜病变
诊断
治疗
最新研究进展
diabetic retinopathy
diagnosis
treatment
latest research progress