阿奇霉素与左氧氟沙星在慢性支气管炎治疗中的应用及评价

Application and evaluation of azithromycin and levofloxacin in the treatment of chronic bronchitis

目的探讨阿奇霉素与左氧氟沙星在慢性支气管炎治疗中的具体运用情况,评价其临床效果。方法 98例慢性支气管炎患者作为研究对象,按照电脑排序的方式随机分为对照组和观察组,每组49例。对照组患者给予单纯的阿奇霉素治疗,观察组患者给予阿奇霉素联合左氧氟沙星治疗。比较两组患者的治疗效果与临床症状缓解时间。结果观察组患者治疗总有效率为95.92%,明显高于对照组的79.59%,差异具有统计学意义(P<0.05)。观察组患者的气促、咳嗽、呼吸困难缓解时间均明显短于对照组,差异具有统计学意义(P<0.05)。结论对慢性支气管炎患者运用阿奇霉素与左氧氟沙星治疗的临床效果显著,临床症状缓解时间较短,值得临床推广与应用。

Objective To discuss the clinical effect of azithromycin and levofloxacin in the treatment of chronic bronchitis.Methods A total of 98 chronic bronchitis patients as study subjects were divided by computer ordering method into control group and observation group,with 49 cases in each group.The control group was treated with simple azithromycin,and the observation group was treated with azithromycin and levofloxacin.The treatment effect and clinical symptom remission time between the two groups was compared.Results The observation group had obviously higher total treatment effective rate as 95.92%than 79.59%in the control group,and the difference was statistically significant(P<0.05).The observation group had obviously shorter shortness of breath,cough,and difficulty breathing remission time than the control group,and their difference was statistically significant(P<0.05).Conclusion Application of azithromycin and levofloxacin in patients with chronic bronchitis shows significant