响应面法优化麦芽糖水解制备5-羟甲基糠醛

Optimization of 5-Hydroxymethylfurfural Preparation from Hydrolysis of Maltose Dehydration by Response Surface Methodology

以麦芽糖为原料,水为溶剂,考察了磷酸、硫酸、乙酸锌和氢氧化钠为催化剂对5-羟甲基糠醛制备的催化效果。研究结果表明:氢氧化钠的催化能力远高于其他催化剂,且用量较少。以5-羟甲基糠醛的收率为衡量标准,采取响应面法对反应条件进行了优化,得到最佳条件为反应温度95.20℃、催化剂氢氧化钠的质量2.25g、反应时间6.17h。在此反应条件下,5-羟甲基糠醛的收率达61.13%。红外谱图分析结果与标准样品谱图一致,表明由麦芽糖成功制备了5-HMF。

The catalytic effects of phosphate,sulfuric acid,zinc acetate and sodium hydroxide catalysts on the preparation of 5-hydroxymethylfurfural(5-HMF)were investigated with maltose as raw material and water as solvent,and the results showed that the catalytic capacity of sodium hydroxide was much higher than that of other catalysts and the dosage was less.Response surface methodology(RSM)was utilized for optimization the reactive conditions with the yield of 5-HMF as yardstick.The optimum values of these factors were found to be as follows:reaction temperature 95.20℃,mass of sodium hydroxide 2.25 g,reaction time 6.17 h.In this case,the yield of 5-hydroxymethylfurfural reached 61.13%.The result of infrared spectrogram analysis was consistent with the standard sample,and 5-HMF was prepared from maltose.