一种基于近红外光谱成像的可穿戴式设备的设计

Design of a Wearable Device Based on Near Infrared Spectrum Imaging

血液动力学一直是研究大脑的一个重要方法。最近几年,近红外光谱成像系统(fNIRS)已经成为人们研究大脑活动的一种重要手段。近红外光谱成像通过测量含氧血红蛋白和脱氧血红蛋白的浓度变化,来反应大脑的活动状态。近红外光谱成像是一种无损伤的检测技术,同时有许多的优点,比如测量速度快、操作简单、在空间和时间方面都有较好的分辨率,所以近红外光谱成像越来越被广泛地运用于各种研究。但是现阶段的近红外光谱成像大部分依然是不可以穿戴式、不可便携的,同时实验者在实验过程中是不可以自由移动的。本文设计了一个低成本、低功耗、可穿戴和支持无线传输的近红外光谱成像系统。这个系统通过发射两种不同波长的近红外光(760 nm和850 nm),测量大脑中血液的含氧血红蛋白和脱氧血红蛋白的浓度变化,计算出大脑的活动变化。我们使用3D打印技术为系统设计了合适的外壳。同时该系统在锂电池供电的情况下可以连续工作数个小时。通过实验证明,该系统可以有效的检测含氧血红蛋白和脱氧血红蛋白的浓度变化并能反应大脑的活动状态。

Hemodynamics has always been an important method of studying the brain.In recent years,functional near-infrared spectroscopy(fNIRS)has been utilized for examining functional brain activity by measuring the changes in the concentrations of oxygenated hemoglobin and deoxyhemoglobin.fNIRS is a noninvasive detection technology.It has many characteristics,such as fast measurement speed,simple operation,and good compromise in both spatial and temporal resolution.Thus,it has been widely used in various studies.However,recent fNIRS is still non-wearable and non-portable,and the the experimenter is not free to move during the experiment.In this work,we designed a low-cost,low power,wearable and wireless fNIRS system.This system detected the changes of brain activity by measuring the concentration of oxygenated hemoglobin and deoxyhemoglobin in the blood using two different wavelengths of near-infrared light(760nm and850nm).Meanwhile,we designed a plastic housing for the optical fiber by3D printing technology.The system can work continuously for several hours under the lithium battery power supply.The results showed that the system can effectively detect the concentration changes of oxygenated hemoglobin and deoxyhemoglobin and can reflect the activity of the brain.