影像学诊断技术在非酒精性脂肪性肝病中的应用价值

Application value of imaging diagnosis in nonalcoholic fatty liver disease

非酒精性脂肪性肝病的病程进展漫长,病变复杂多样,临床分期较为困难。肝穿刺病理是诊断脂肪肝的金标准,但在临床应用过程中受到诸多限制,因此如何通过无创手段准确检测脂肪肝是目前研究热点。影像学检查可定性、定量评估肝脂肪变性及纤维化,具有较好的应用前景。重点介绍了近年来非酒精性脂肪性肝病无创诊断在影像学方面的相关进展。

Nonalcoholic fatty liver disease(NAFLD)is a chronic disease with complex lesions,and it is difficult to determine the clinical stage.Liver biopsy is still the gold standard for the diagnosis of NAFLD;however,its clinical application is limited by various factors.Therefore,noninvasive methods for the accurate diagnosis of NAFLD are research hotspots at present.Imaging examinations help to achieve qualitative and quantitative evaluations of hepatic steatosis and fibrosis and thus has a promising future in clinical practice.This article summarizes the research advances in the imaging diagnosis of nonalcoholic fatty liver disease in recent years.