左氧氟沙星联合乳酸杆菌阴道胶囊治疗衣原体阳性宫颈炎患者的疗效与安全性

Efficiency and safety of levofloxacin combined with lactobacillus vaginal capsule in treating patients with chlamydia-positive cervicitis

目的探讨左氧氟沙星联合乳酸杆菌阴道胶囊治疗衣原体阳性宫颈炎患者的疗效与安全性。方法将200例衣原体阳性宫颈炎患者随机分为观察组与对照组。对照组患者采用左氧氟沙星治疗,观察组在对照组基础上使用乳酸杆菌阴道胶囊。比较2组患者临床疗效、衣原体转阴率、阴道清洁程度、复发情况以及不良反应发生率。结果观察组患者治疗总有效率89. 00%,显著高于对照组76. 00%(P <0. 05);观察组患者转阴率显著高于对照组(P <0. 05)。治疗后,2组患者阴道清洁度评分均显著降低,且观察组患者阴道清洁度评分显著高于对照组(P <0. 05)。2组患者不良反应发生率与复发率比较,差异无统计学意义(P> 0. 05)。结论左氧氟沙星联合乳酸杆菌阴道胶囊治疗衣原体阳性宫颈炎患者安全有效。

Objective To explore the safety and efficiency of levofloxacin combined with lactobacillus vaginal capsules in treating patients with chlamydia-positive cervicitis.Methods A total of200patients with chlamydia-positive cervicitis were randomly divided into observation group and control group.The control group was treated with levofloxacin,while the observation group was treated with lactobacillus vaginal capsule on the basis of the control group.The clinical efficiency,negative conversion rate of chlamydia,vaginal cleanliness,recurrence condition and incidence rate of adverse reactions were compared between two groups.Results The total effective rate of the observation group was89.00%,which was significantly higher than76.00%of the control group(P<0.05).The negative conversion rate of the observation group was significantly higher than that of the control group(P<0.05).After treatment,the vaginal cleanliness scores in both groups significantly reduced,and the vaginal cleanliness score of the observation group was significantly higher than that of the control group(P<0.05).There were no significant differences in the incidence rate of adverse reactions and recurrence rate between the two groups(P>0.05).Conclusion Levofloxacin combined with lactobacillus vaginal capsule is effective and safe in treating patients with chlamydia-positive cervicitis.