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早期应用鼻塞持续正压通气治疗新生儿呼吸窘迫综合征的疗效观察 被引量:13

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摘要 新生儿呼吸窘迫综合征(neonatalrespiratorydistresssyndrome,NRDS)又称肺透明膜病(hyalinemembranedisease,HMD),较多见于早产儿,多由于肺发育不成熟,缺乏肺表面活性物(pulmonarysurfactant,PS)引起呼吸功能不全,临床表现为生后不久出现呼吸窘迫并呈进行性加重[1]。目前,NRDS的治疗主要包括外源性PS替代治疗和机械通气(mecharni?鄄calventilation,MV)辅助呼吸治疗。PS替代疗法虽然提高了NRDS的治愈率、降低了患儿死亡率,但近年来该类患儿肺功能发育不全的临床报道也随之增多[2]。且PS与MV治疗均需气管插管,为有创性治疗,可导致患儿肺损伤,存在肺出血、肺部感染及气胸等并发症[3]。
作者 刘琳美
出处 《中国药物与临床》 CAS 2018年第12期2219-2221,共3页 Chinese Remedies & Clinics
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