他巴唑与丙基硫氧嘧啶在甲亢治疗中的应用对照

An Application Comparison Study of the Treatment of Hyperthyroidism With Methimazole and Propylthiazolam

目的对照探讨他巴唑与丙基硫氧嘧啶在甲亢治疗中的应用效果。方法选取我院80例甲亢患者,随机分为对照组与观察组,均为40例,对照组应用丙基硫氧嘧啶治疗,观察组应用他巴唑治疗,对比两组的治疗效果。结果观察组的总有效率(95.0%)高于对照组(77.5%),观察组患者用药后的甲状腺激素水平优于对照组,观察组的不良反应发生率(5.0%)低于对照组(20.0%),各组差异均具有统计学意义(P<0.05)。结论他巴唑在甲亢治疗中的应用效果优于丙基硫氧嘧啶,能有效调节甲状腺激素水平,且不良反应较少,可作为当前临床治疗甲亢的理想药物。

Objective To compare the application efficacy of methimazole and propylthiazolam in the treatment of hyperthyroidism.Methods 80 cases of patients selected with hyperthyroidism in our hospital were randomly divided into the control group and the observation group,all of which were 40 cases,the control group was treated with propylthiazolam,the observation group was treated with methimazole,and the therapeutic effect of the two groups was compared.Results The total effective rate of the observation group(95.0%)was higher than that of the control group(77.5%).After medication,the thyroid hormone level in the observation group was better than that of the control group.The incidence of adverse reactions in the observation group(5.0%)was lower than that of the control group(20.0%),and the differences were all significant(P<0.05).Conclusion The effect of methimazole in hyperthyroidism is better than that of propylthiazolam.It can effectively regulate the level of thyroid hormone and has less adverse reactions.It can be used as an ideal drug for the treatment of hyperthyroidism.