早期先兆流产合并绒毛膜下血肿的影响因素及中医证型分布规律

Influencing factors of early threatened abortion complicated with subchorionic hematoma and distribution principle of TCM syndromes

目的探讨早期先兆流产合并绒毛膜下血肿的影响因素,及中医证型在早期先兆流产合并绒毛膜下血肿患者不同孕周的分布规律。方法选取2017年3月～2018年3月期间江西省妇幼保健院确诊的100例早期先兆流产合并绒毛膜下血肿并住院治疗的患者为研究组,另选择100例本院待产人群中孕早期无先兆流产症状者为对照组。比较两组不良生活习惯(包括接触化学污染物、严重负面情绪、服用激素药物)、流产次数及早期先兆流产合并绒毛膜下血肿的中医证型分布规律(包括血瘀阻滞证、湿热内蕴证、阴虚血热证、血热证、气血虚弱证、肾气亏虚证)。结果研究组不良生活习惯明显高于对照组(P<0.05);研究组流产次数与对照组比较有明显差异(P<0.05);早期先兆流产合并绒毛膜下血肿患者不同孕周的中医证型分布规律差异有统计学意义(P<0.05)。结论患者的不良生活习惯和流产次数是早期先兆流产合并绒毛膜下血肿的主要影响因素;孕妇的孕周和早期先兆流产合并绒毛膜下血肿的中医证型分布有密切关系,且肾气亏虚证是早期先兆流产合并绒毛膜下血肿中医证型的主要证型。

Objective To investigate the influencing factors of early threatened abortion complicated with subchorionic hematoma,and the distribution principle of TCM syndromes in the patients with early threatened abortion complicated with subchorionic hematoma in different gestational weeks.Methods A total of100patients with early threatened abortion complicated with subchorionic hematoma diagnosed and hospitalized in Jiangxi Women and Children's Hospital from March2017to March2018were selected as the study group.Another100pregnancy women in their early trimester without symptoms of early threatened abortion in our hospital were selected as the control group.The negative life habits(including exposure to chemical pollutants,severe negative emotions,taking hormonal drugs),the number of abortions and the distribution principle of TCM syndromes in early threatened abortion complicated with subchorionic hematoma(including blood stasis syndrome,dampness and heat syndrome,yin deficiency and blood heat syndrome,blood heat syndrome,qi and blood deficiency syndrome,kidney qi deficiency syndrome)were compared between the two groups.Results The negative life habits in the study group were significantly more than those in the control group(P<0.05);the number of abortions in the study group was significantly different from that in the control group(P<0.05);there was statistically significant differences in the distribution principle of TCM syndromes in the patients with early threatened abortion complicated with subchorionic hematoma in different gestational weeks(P<0.05).Conclusion The negative life habits and frequency of abortion are the main influencing factors for early threatened abortion complicated with subchorionic hematoma;there is a close relationship between the gestational weeks of pregnant women and the distribution of TCM syndromes in early threatened abortion complicated with subchorionic hematoma.The kidney qi deficiency syndrome is the main syndrome type of early threatened abortion complicated with subchorionic hematoma.