莫沙必利致嗜酸性粒细胞增多一例

One case of eosinophilia caused by mosapride

莫沙必利作为消化道促动力药物,不良反应发生率低,尤其应用后出现嗜酸性粒细胞增多的报道极为罕见。本文报告1例我院收治的脑干出血恢复期患者鼻饲枸橼酸莫沙必利分散片溶解液后出现嗜酸性粒细胞增多,经停该药及抗过敏治疗后痊愈出院。莫沙必利作为临床常用药物,在使用时如出现嗜酸性粒细胞增多,应警惕药物不良反应可能,妥善处理。

Mosapride,as a gastroprokinetic agent,has a low incidence of adverse reactions,especially the reports of eosinophilia are extremely rare.A case of convalescent brainstem hemorrhage in our hospital was reported.After nasal feeding of mosapride citrate dispersible tablets,eosinophils increased.The patient was cured and discharged after treatment with antianaphylaxis and discontinuation of mosapride.As a common clinical drug,mosapride should be alert to the possibility of drug allergy reaction if eosinophilia occurs.