幽门螺杆菌胃炎的诊断与治疗

Diagnosis and Treatment of Helicobacter pylori Gastritis

胃炎系指任何病因引起的胃黏膜炎症,常伴有上皮损伤和细胞再生。中国是消化道疾病高发国,胃炎是最常见的消化道疾病之一。根据病情缓急和病程长短,胃炎一般分为急性胃炎和慢性胃炎。幽门螺杆菌(Hp)胃炎是由Hp感染诱发的慢性活动性胃炎。Hp胃炎患者很可能发生消化性溃疡、胃癌等严重疾病,部分患者有消化不良症状,这些疾病严重影响患者的生活质量,给社会和家庭带来沉重的疾病负担和经济压力。国际疾病分类第11版(ICD-11)对胃炎的分类主要基于病因以及特殊的病理生理学原则,并指出Hp感染是胃炎的主要病因。本文对Hp胃炎的病因以及针对病因的诊断和治疗进展作一综述。

Gastritis refers to the inflammation of gastric mucosa caused by any etiology,often accompanied by epithelial damage and cell regeneration.China is a country with a high morbidity of digestive diseases,and gastritis is one of the most common digestive diseases.According to the severity and course of the disease,it is generally divided into acute gastritis and chronic gastritis.Helicobacter pylori(Hp)gastritis is a chronic active gastritis induced by Hp infection.Patients with Hp gastritis are likely to develop severe diseases such as peptic ulcer and gastric cancer,some patients have dyspeptic symptoms.These diseases seriously affect the quality of life of patients,and bring heavy disease burden and economic pressure on society and families.In the11th Revision of the International Classification of Diseases(ICD-11),the classification of gastritis is mainly based on the etiology and special pathophysiological principles,and it points out that Hp infection is the main cause of gastritis.In this article,the etiology of Hp gastritis,as well as the diagnosis and treatment based on the etiology were reviewed.