慢性阻塞性肺疾病与老年综合征--老年科医师的视角

Geriatric syndromes in chronic obstructive pulmonary disease:viewpoint from geriatrician

慢性阻塞性肺疾病(COPD)是我国常见和重要危害国人身体健康的慢性呼吸道疾病。随着年龄的增长,慢阻肺患病率呈指数型增加,其亦是一种增龄相关性疾病(老年病)。衰弱和肌少症是老年医学科临床上重要的两种老年综合征,往往与慢阻肺患者的临床不良结局密切相关。本文就衰弱和肌少症的临床评估工具,慢阻肺时两种老年综合征的流行病学,生物学机制及可能的干预策略等做一述评。

Chronic obstructive pulmonary disease(COPD),one of themost common and important chronic respiratory disease,is a great threat for public health in China.The prevalence of COPD increases exponentially in advancing age.COPD is also an age-related disease.Frailty and sarcopenia are clinically important geriatric syndromes in geriatric medicine.The two syndromes are closely related to poor outcomes in patients with COPD.This editorial is on clinical assessment tools of frailty and sarcopenia,epidemiological evidence and biological mechanism of the two syndromes in COPD and potential intervention strategies.