急腹症早期应用奈福泮镇痛效果及对诊断的影响

Analgesia effect of early application of nefopam and its effect on the accuracy of diagnosis in acute abdominal pain

目的探讨急腹症早期使用奈福泮的镇痛效果及对诊断准确性的影响。方法回顾性研究西南医科大学附属医院急诊医学部2017年2月～2017年7月接诊的符合条件的急腹症患者67例,分为镇痛组(32例)与安慰剂组(35例)。对比分析早期使用奈福泮对急腹症诊断准确性的影响及镇痛效果。结果镇痛组和安慰剂组诊断准确率分别为87.5%和91.1%(X^2=0.012,P=0.9),差异无统计学意义(P<0.05);两组用药后0.5、1、2小时VSA评分中位数分别为4,6、2,6、5,6,两组镇痛效果差异有统计学意义(P=0.01,P=0.01,P=0.031)。结论急腹症早期使用奈福泮镇痛不影响诊断准确性,奈福泮起效快,作用时间较长,镇痛效果适中,可用于急腹症早期镇痛。

Objective To investigate effects of the analgesic effect and its effect on the accuracy of diagnosis.Methods A retrospective study was performed on 67 cases of acute abdominal pain treated by the department of emergency medicine t of The Affiliated Hospital of Southwest Medical University from February 2017 to July 2017.We compared the effect and analgesic effect of the early use of nefopam on the diagnostic accuracy of acute abdomen.Results The accuracy of the diagnosis accuracy for the pain control group and the placebo were 87.5%and 91.1%(x2=0.012,P=0.9).We have found the no significant difference between the two groups.After treatment,the median of 0.5 hours,1 hour and 2 hours of VSA score was 4,6.2,6;5,6(P=0.01,P=0.01,P=0.031)in the two groups.Conclusion The early use of Nefopam in acute abdomen does not affect the accuracy of the diagnosis.Nefopam is effective and has a long working time.Because of moderate analgesia effect,it’s suitable for early pain relief of acute abdomen.