负压封闭引流术联合抗生素骨水泥治疗创伤性骨髓炎的疗效观察

Clinical application of vacuum sealing drainage combined with antibiotic bone cement in traumatic osteomyelitis treatment

目的探讨负压封闭引流术(VSD)联合抗生素骨水泥治疗创伤性骨髓炎的临床效果。方法选择2013年7月～2016年12月我院收治的108例创伤性骨髓炎患者为研究对象,所有患者按入院顺序分为对照组(54例)和观察组(54例)。对照组采用传统的治疗方法对病灶进行清创刮除灭活抗生素骨水泥填充,观察组采用VSD联合抗生素骨水泥进行治疗,比较两组患者的治疗效果。结果观察组C反应蛋白变化率高于对照组;术后对照组6、12、24、48、72h的VAS评分均高于观察组;观察组治疗有效率、治愈率均高于对照组,而复发率和再次清创率均低于对照组,差异均具有统计学意义(P<0.05)。结论 VSD联合抗生素骨水泥治疗创伤性骨髓炎,对病灶进行充分的引流,能有效避免传统治疗方案带来的弊端,可明显降低复发率和再次清创率。

Objective To investigate the clinical effect of vacuum sealing drainage(VSD)combinedwith antibiotic cement in traumatic osteomyelitis.Methods 108 patients of traumatic osteomyelitis were treated in our hospital from July 2013 to December 2016 and were analyzed.All patients were divided into observation group(54 cases)and control group(54 cases)according to different treatment methods.The control group was treated with antibiotic bone of traumatic osteomyelitis.The observation group was treated with VSD combined with antibiotic bone.The patient’s treatment effects were compared.Results The C reactive protein changes rate of observation group was higher than that of the control group.The VAS of the control group at 6h,12h,24h,48h and 72h were higher than those in the observation group.The effective rate and cure rate in the observation group were higher than that of the control group.The recurrence rate and debridement rate in the observation group were far lower than that of the control group.The differences were statistically significant(P<0.05).Conclusion VSD combined with antibiotic bone cement in the treatment of traumatic osteomyelitis can effectively avoid the drawbacks of traditional treatment and drainage adequately,and significantly reduce the recurrence rate.