规范化超声诊断妊娠11～13^(+6)周胎儿神经管畸形的临床价值

The clinical value of standardized ultrasound in diagnosing fetal neural tube defects during 11～13^(+6) weeks' gestation

目的探讨超声诊断妊娠11～13^(+6)周胎儿神经管畸形(NTDs)的临床价值。方法选择2014年12月～2016年12月于南充市中心医院产检的2638例妊娠11～13^(+6)周孕妇,进行规范化早孕期产前超声检查,追踪检出的NTDs胎儿及其余胎儿的引产结果和妊娠结局。结果妊娠11～13^(+6)周超声NTDs总检出率71.43%(10/14),无脑畸形检出率为100%(3/3),露脑畸形检出率100%(1/1),脑膜脑膨出检出率100%(2/2),全前脑畸形检出率50%(1/2),脊柱裂及脊髓脊膜膨出检出率50%(3/6)。NTDs异常声像表现均可在存留标准图像中进行观察和诊断。结论规范化超声检查对妊娠11～13^(+6)周严重NTDs胎儿的确诊率高,可在临床推广应用。

Objective To analyze the clinical value of standardized ultrasound in diagnosing fetal neural tube defects(NTDs)during 11~13^+6 weeks’gestation.Methods During December 2014 to December 2016,2638 pregnant women during 11~13^+6 weeks'gestation from Nanchong Central Hospital were detected with standardized ultrasound.Keep track of NTDs fetuses induced labor results and normal fetuses pregnancy outcome.Results The total detection rate of NTDswas 71.43%during 11~13^+6 weeks’gestation.Tthe detection rates of anencephaly,exencephaly,meningoceles and encephalocele,holoprosencephaly and rachischisiswere 100%,100%,100%,50%and 50%,respectively.The Ultrasonic features of NTDswere observed and diagnosed in standardized views.Conclusion The standardized ultrasound during 11~13^+6 weeks’gestation is effective in detection of seriousNTDs.