无痛胃镜检查中不同麻醉方法的临床效果观察

Clinical observation of different anesthesia methods in painless gastroscopy

目的:探讨无痛胃镜检查中使用不同麻醉剂的效果及安全性。方法:随机抽取行无痛胃镜检查患者1 418例,随机分为4组。Ⅰ组为使用丙泊酚注射;Ⅱ组注射咪唑安定后再注射丙泊酚;Ⅲ组先注射舒芬太尼,之后注射丙泊酚;Ⅳ组同样是先注射盐酸钠布啡后再注射丙泊酚。结果:4组患者的试验差异有统计学意义(P<0.05)。其中Ⅰ组丙泊酚药剂的用量与其他3组相比有明显增加(P<0.05);Ⅲ组和Ⅳ组在检查后的生命体征大于Ⅰ组和Ⅱ组(P<0.05)。结论:在无痛胃镜检查中均可使用以上4种麻醉方法,其中舒芬太尼与丙泊酚的联合使用以及盐酸钠布啡与丙泊酚联合使用的注射方法十分稳定。

Objective:To investigate the efficacy and safety of different anesthetics in painless gastroscopy.Methods:1418 patients with painless gastroscopy were randomly divided into four groups:groupⅠwas injected with propofol;groupⅡwas injected with midazolam and then propofol;groupⅢwas injected with sufentanil and then propofol;groupⅣwas injected with sodium hydrochloride and buprofen before propofol.Results:The difference between the 4 groups was statistically significant(P<0.05).The dosage of propofol in groupⅠwas significantly higher than that in other three groups(P<0.05),and the vital signs in groupⅢand groupⅣwere higher than those in groupⅠand groupⅡ(P<0.05).Conclusion:All the above four anesthesia methods can be used in painless gastroscopy.Sufentanil combined with propofol and sodium hydrochloride combined with ibuprofen and propofol injection method is very stable.