高危型HPV DNA和HPV RNA检测分别联合TCT应用于宫颈癌初筛的临床意义

Clinical significance of high risk HPV DNA and HPV RNA detection combined with TCT respectively in screening of cervical cancer

目的:研究高危型HPV DNA和HPV RNA检测分别联合宫颈液基细胞学检测(TCT)应用于宫颈癌筛查的意义。方法:收治宫颈癌患者160例,随机分为A组和B组。A组采用HPV RNA联合TCT,B组采取HPV DNA联合TCT,比较两组检出率及诊断有效率。结果:A组检出率和诊断有效率明显低于B组(P<0.05)。结论:高危型HPV DNA联合TCT应用于宫颈癌初筛的效果优于HPV RNA联合TCT,临床价值较高。

Objective:To explore the clinical significance of high risk HPV DNA and HPV RNA detection combined with thinprep cytologic test(TCT)respectively in screening of cervical cancer.Methods:160 patients with cervical cancer were selected,they were randomly divided into the A group and the B group,the A group received HPV RNA combined with TCT test,the B group received HPV DNA combined with TCT detection.We compared the detection rate and diagnostic efficiency of the two groups.Results:In the A group,the detection rate and diagnostic efficiency were significantly lower than those in the B group(P<0.05).Conclusion:The effect of high-risk HPV DNA combined with TCT on cervical cancer screening was better than that of HPV RNA combined with TCT,the clinical value was relatively high.