上海嘉定区甲状腺癌的相关危险因素研究

Study of risk factors related to thyroid cancer in Jiading District, Shanghai

目的 :研究上海嘉定区甲状腺癌的相关危险因素,为甲状腺癌的防治提供依据。方法 :以2007年1月1日至2016年12月30日被确诊的140例上海嘉定区甲状腺癌患者为病例组,其中男性42例,女性98例,平均年龄(48.54±12.88)岁。按1:1配对招募140例非甲状腺癌对象作为对照组,其中男性42例,女性98例,平均年龄(47.11±12.58)岁。采用自行设计问卷进行统一调查。结果 :单因素分析结果显示,病例组和对照组在体重指数、口味、食用海洋动物性食品、食用腌制食品、做菜放盐顺序、处事态度、性格、婚姻生活情况、经常熬夜、饮茶、爱生闷气、有肿瘤家族史方面的差异有统计学意义(P <0.05)。COX回归分析发现口味重、爱生闷气、肿瘤家族史是甲状腺癌的危险因素。结论:肿瘤家族史、口味重、爱生闷气是与甲状腺癌独立相关,需通过健康宣教让人们更多地关注甲状腺癌,避免相关危险因素的暴露。

Objective:To study the risk factors related to thyroid cancer in Jiading District,Shanghai for providing evidence for the prevention and treatment of thyroid cancer.Methods:A total of140confirmed cases of thyroid cancer in Jiading District,Shanghai,from January1,2007to December30,2016were as a case group,including42males and98females,with an average age of(48.54±12.88)years.According to1:1matching,140cases of non thyroid cancer were recruited as a control group,including42males and98females,with an average age of(47.11±12.58)years old.A self-designed questionnaire was used to conduct the unified survey.Results:Univariate analysis results showed that there were statistically significant differences in body mass index,taste,edible marine animal food,edible preserved food,cooking and salting order,attitude,personality,marriage and life,staying up late,drinking tea,sulking and the family history of tumors between the case group and the control group(P<0.05).COX regression analysis showed that heavy taste,depression and family history of tumors were risk factors for thyroid cancer.Conclusion:Family history of tumors,heavy taste and love sulking are independent correlation of thyroid cancer,and people should pay more attention to thyroid cancer through health education so as to avoid exposure of related risk factors.