综合ICU内腹腔感染相关性脓毒症患者的临床特征分析

Clinical characteristics of patients with abdominal infection related sepsis in integrated ICU

目的 探讨综合重症监护病房(ICU)腹腔感染相关性脓毒症患者的临床特征。方法 回顾分析2013年1月至2018年1月资料,通过病例对照研究比较腹腔感染相关性脓毒症(69例)与腹腔感染非脓毒症患者(138例)的临床表现,探讨腹腔感染相关性脓毒症患者的临床特征。结果 1.腹腔感染相关性脓毒症患者病死率及平均住院费用较对照组高[43.5%比11.6%,(0.93±0.24)万元/天比(0.57±0.13)万元/天];2.低白蛋白的腹腔感染患者、合并急性肾功能损伤的腹腔感染患者更易发生腹腔感染后相关性脓毒症(44.9%比13.8%,59.4%比20.3%);3.感染源控制措施延迟可能是腹腔感染相关性脓毒症的重要原因(11.6%比2.8%)。结论 腹腔感染相关性脓毒症患者病死率高,花费高,应积极纠正低白蛋白血症,明确病因后应尽快采取感染源控制措施。

Objective To investigate the clinical characteristics of patients with abdominal infection related sepsis in integrated ICU.Methods A retrospective analysis was made on 69 patients with abdominal infection related sepsis and 138 patients with abdominal infection without sepsis admitted in the ICU of our hospital from January 2013 to January 2018,the clinical characteristics of patients with abdominal infection related sepsis were investigated.Results 1.The mortality and mean hospitalization expenses in patients with abdominal infection related sepsis were higher than those in the control group[43.5%vs.11.6%,(0.93±0.24)×104 Yuan/d vs.(0.57±0.13)×104 Yuan/d];2.abdominal infection patients with low albumin and acute kidney injury were more likely to have sepsis(44.9%vs.13.8%,59.4%vs.20.3%);3.the delay of infection source control measures may be an important cause of abdominal infection related sepsis(11.6%vs.2.8%).Conclusion The mortality rate of abdominal infection related sepsis is high and the cost is high,and the control measures of infection source should be taken as soon as possible after the pathogeny is clear.