2017—2018年流感流行季节佛山市神经氨酸酶抑制剂使用情况分析

Usage analysis of neuraminidase inhibitors during influenza epidemic period in Foshan from 2017 to 2018

目的 掌握佛山市2017—2018年流感流行季医院门诊、住院神经氨酸酶抑制剂使用情况。方法 使用白噪声检验门诊流感样病例用药量、住院肺炎用药量是否存在时间差异,使用相关分析分析门诊神经氨酸酶抑制剂与门诊流感样病例数量、门诊流感样病例禽类接触情况的关系,分析住院肺炎病例神经氨酸酶抑制剂使用量与住院肺炎数、ICU病例数的关系。结果 门诊神经氨酸酶抑制剂、住院肺炎神经氨酸酶抑制剂使用量存在一定的季节性分布,白噪声检验结果的Box-Ljung Q值分别为110.47和52.509。门诊用药与门诊流感样病例数量关系比较强(r=0.991),而与住院肺炎病例数量关系相对较弱(r=0.731)。结论 佛山市各级医疗机构门诊医师对于门诊流感样病例、住院肺炎的流感患者用药较为清晰。

Objective To have some ideas of the usage of neuraminidase inhibitors during influenza epidemic period in Foshan hospital.Methods White noise test was used to test the usage of neuraminidase inhibitor distribution randomly;and the correlation test was used to analyze the relationship between the usage of neuraminidase inhibitors for outpatient influenza like illnesses(ILI)and inpatient pneumonia.Results The usages of neuraminidase inhibitors both in inpatient and outpatient had seasonal fluctuation.The Box-Ljung Q values of white noise were 110.47 and 52.509,respectively.The usage of neuraminidase inhibitors for outpatient ILI(r=0.991)had higher association than inpatient pneumonia(r=0.731).Conclusion The awareness of neuraminidase inhibitor prescriptions both on outpatient ILI and inpatient pneumonia are clear.