正常肾脏在不同场强下体素不相干运动MRI研究

A comparative study of IVIM-DWI on normal kidney in healthy adults between 1.5T and 3.0T MR scanner

目的:探讨不同场强条件对健康成人肾脏体素不相干运动(IVIM)DWI定量参数值的影响。方法:30例健康志愿者在24h内分别在1.5T和3.0T MR扫描仪上进行扫描序列和参数完全相同的IVIM-DWI扫描,比较不同场强下肾实质的灌注参数(D、D*和f)值的差异。结果:3.0T场强条件下左、右侧肾实质的D值均大于1.5T、D*值均小于1.5T,差异均有统计学意义(P<0.05);两种场强条件下f值的差异无统计学意义(P>0.05)。在相同场强条件下,1.5T时左肾实质的D值大于右肾(P<0.05);而3.0T时双肾实质D值的差异无统计学意义(P>0.05);1.5T时不同性别组间双肾的D、D*和f值的差异均无统计学意义(P>0.05),而3.0T时男性组双肾的f值大于女性组(P<0.05)。结论:肾脏IVIM-DWI定量参数值的测量受到场强变化的影响,其可靠性和可行性需建立在相同场强及扫描参数统一的基础上。

Objective:To compare the D,D*and f values of healthy kidneys in different field strengths and investigate whether an IVIM-DWI conclusion was applicable to different field strengths.Methods:30 healthy volunteers underwent kidney IVIM-DWI twice using the same scan sequences and parameters at 1.5T and 3.0T MR scanners within 24 hours.The differences of D,D*,and f values were compared.Results:The D values of the left and right renal parenchyma at the 3.0T MR scanner were significantly greater than those at the 1.5T MR scanner(P<0.05),D*values were less than those at 1.5T MR scanner(P<0.05),while The f values had no significant difference between them(P>0.05).Under 1.5T field strength,D value of left renal parenchyma was higher than that of right kidney with statistically significant difference,while the D value of left and right renal parenchyma has no difference at 3.0T MR scanner.The D,D*and f values in male and female groups were not significantly different(P>0.05)at 1.5T MR scanner,while f value in male group was higher than that in female group at 3.0T MR scanner(P<0.05).Conclusion:The quantitative parameter values of kidney IVIM-DWI were affected by different field strengths.Their reliability and feasibility should be based on the same field strength and scan parameters.