摘要
创伤性脑损伤后的生物标志物具有定性定量评估创伤性脑损伤程度、预测病人转归的作用,文章对S100B蛋白、神经元特异性烯醇化酶、胶质纤维酸性蛋白、泛素碳末端水解酶L1、神经微丝蛋白轻链5种生物标志物在创伤性脑损伤病情评估及预后判断等方面进行综述。
Many biomarkers in traumatic brain injury can qualitatively and quantitatively assess the severity and predict the outcomes of the traumatic brain injury.The article presents a review of studies on the efficacy of traumatic brain injury biomarkers,such as S100 calcium binding protein beta subunit(S100B),neuron-specific enolase(NSE),glial fibrillary acidic protein(GFAP),ubiquitin carboxy-terminal hydrolase-L1(UCH-L1),neurofilament light chain(NF-L),in making disease assessment and prognosis.
作者
吴文天
肖国民
WU Wen-tian;XIAO Guo-min(Department of Neurosurgery,The Affiliated Hospital of Hangzhou Normal University,Hangzhou 310015,China)
出处
《健康研究》
CAS
2018年第6期657-660,共4页
Health Research
关键词
创伤性脑损伤
生物标志物
预后
traumatic brain injury
biological markers
prognosis
