点阵铒激光联合脉冲燃料激光治疗痤疮后增生性瘢痕的临床研究

Clinical study on fractional erbium laser combined with pulsed dye laser in treating hyperplastic scar after acne

目的观察对痤疮后增生性瘢痕患者予以点阵铒激光和脉冲燃料激光联合治疗的临床效果。方法临床选择2016年4月至2017年7月在该院就诊的痤疮后增生性瘢痕患者90例,根据治疗方式的不同分为观察组(n=46)和对照组(n=44)。观察组进行点阵铒激光和脉冲燃料激光联合治疗,对照组仅予以点阵铒激光治疗。比较两组治疗后的临床效果及治疗前后的痤疮特异性量表评分。随访3个月,比较两组治疗后的不良反应发生情况。结果观察组总有效43例(93.5%),对照组总有效30例(68.2%),两组临床效果比较差异有统计学意义(P<0.05)。观察组治疗后的痤疮特异性量表各指标均高于对照组,差异有统计学意义(P<0.05)。两组发生皮肤红斑、色素脱失、灼痛感等不良反应比较差异无统计学意义(P>0.05)。结论对痤疮后增生性瘢痕患者予以点阵铒激光和脉冲燃料激光联合治疗可提高其生存质量。

Objective To observe the clinical effect of erbium fractional laser combined with pulsed dye laser in treating hyperplastic scar after acne.Methods Ninety patients with hyperplastic scar after acne treated in this hospital from April 2016 to July 2017 were clinically selected and divided into the observation group(n=46)and control group(n=44)according to the different treatment methods.The observation group conduct the erbium fractional laser combined with pulsed dye laser treatment;the control group just took the fractional erbium laser treatment.The clinical effects after treatment were compared between the two groups and the Qol-acne scale scores were compared between before and after treatment.After three months of follow-up,the occurrence situations of adverse reactions were compared between the two groups.Results There were total 43 effective cases(93.5%)in the observation group and total 30 effective cases(68.2%)in the control group.The difference in clinical effects between the two groups was statistically significant(P<0.05).The scores of various indexes of the Qol-acne scale after treatment in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The adverse reactions like skin erythema,depigmentation and sense of burning had no statistically significant difference between the two groups(P>0.05).Conclusion The combined treatment of fractional erbium laser and pulsed dye laser in treating hyperplastic scar after acne can improve the patient′s quality of life.