低分子肝素对老年粗隆间骨折患者术前深静脉血栓的预防作用

Preventive effect of Low Molecular Weight Heparin on preoperative deep vein thrombosis in elderly patients with intertrochanteric fracture

目的探讨单纯应用低分子肝素对老年粗隆间骨折患者术前深静脉血栓的预防作用。方法将2015年8月～2018年7月冀中能源峰峰集团有限公司总医院收治的所有符合纳入标准的老年粗隆间骨折患者共52例作为试验组,入院后即给予低分子肝素预防深静脉血栓。将2012年12月～2014年7月收治的未采取低分子肝素进行深静脉血栓预防的老年粗隆间骨折患者共45例作为对照组,分别计算试验组及对照组患者术前深静脉血栓的发病率,并采用SPSS 21.0软件对两组术前深静脉血栓的发病率及深静脉血栓类型分布情况进行统计学分析。结果试验组术前深静脉血栓发病率[13.5%(7/52)]与对照组[24.4%(11/45)]比较,差异无统计学意义(P=0.165)。两组深静脉血栓类型分布情况比较,差异无统计学意义(P=1.000)。结论单纯采用低分子肝素预防术前老年粗隆间骨折患者深静脉血栓的效果可能不明显,还需要联合应用其他物理方法来进行预防。

Objective To investigate the preventive effect of Low Molecular Weight Heparin on preoperative deep vein thrombosis in elderly patients with intertrochanteric fracture.Methods Fifty-two elderly patients with intertrochanterteric fracture in accordance with the inclusion criteria admitted to Jizhong Energy Fengfeng Group General Hospital from August2015to July2018were selected as the experimental group,they were given Low Molecular Weight Heparin to prevent preoperative deep venous thrombosis after admission.45elderly patients with intertrochanterteric fracture without using Low Molecular Weight Heparin to prevent preoperative deep venous thrombosis from December2012to July2014were selected as the control group.The incidence of preoperative deep venous thrombosis in the two groups was calculated.SPSS21.0sofyware was used to analyze the incidence of preoperative deep venous thrombosis and the type distribution of deep venous thrombosis between the two groups.Results The incidence of preoperative deep venous thrombosis had no significant difference between the experimental group[13.5%(7/52)]and the control group[24.4%(11/45)](P=0.165).There was no significant difference in the type distribution of deep vein thrombosis between the two groups(P=1.000).Conclusion The effect of using only Low Molecular Weight Heparin in prevention of deep vein thrombosis in elderly patients with intertrochanteric fracture may not be obvious.Other physical methods still need to be combined for prevention.