分析桃红四物汤、手法复位夹板或石膏固定治疗四肢闭合性骨折及影响机体炎性细胞因子的实际效果

Analysis of Peach Blossom Tang, Manual Reduction Splint or Plaster Fixation Therapy of Closed Fracture of Extremities and Practical Effect of Inflammatory Cytokines in the Body

目的探讨桃红四物汤应用于经手法复位后夹板或石膏固定治疗的四肢闭合性骨折患者临床实际效果及对其机体炎性细胞因子的影响情况。方法方便选取该院于2016年12月—2018年1月期间收治的58例四肢闭合性骨折患者作为该次研究对象,利用随机数字表法将其均分为研究组(n=29)、对照组(n=29)。对照组四肢闭合性骨折患者接受常规保守治疗,研究组四肢闭合性骨折患者在常规治疗基础上加用桃红四物汤。记录两组治疗效果及治疗前后炎性细胞因子水平变化情况。结果两组四肢闭合性骨折患者治疗前VAS量表评分、炎性细胞因子水平对比差异无统计学意义(P>0.05),治疗后两组VAS量表评分、IL-6及TNF-α水平均较之前有所下降,研究组上述指标改善幅度优于对照组(P<0.05),研究组骨折愈合时间(35.13±2.17)个月显著少于对照组(45.62±2.35)个月,差异有统计学意义(t=17.660 7,P<0.05)。结论应用手法复位夹板或石膏固定治疗四肢闭合性骨折基础上加用桃红四物汤可有效促进患者骨折尽快愈合,有利于降低机体炎症细胞因子水平,对保障患者疗效及预后均具有积极意义。

Objective To study the peach blossom tang,manual reduction splint or plaster fixation therapy of closed fracture of extremities and practical effect of inflammatory cytokines in the body.Methods58cases of patients with closed fracture of extremities admitted and treated in our hospital from December2016to January2018were convenient selected and randomly divided into two groups with29cases in each,the control group used the routine conservative therapy,while the research group used the peach blossom tang on the basis of the control group,and the treatment effect,and changes of inflammatory factor level before and after treatment of the two groups were recorded.Results The differences in the VAS scale score and inflammatory cell factor level between the two groups the difference were not statistically significant(P>0.05),after treatment,the VAS scale score,IL-6,TNF-αlevels after treatment decreased,and the improvement range of the above indexes in the research group was better than that in the control group(P<0.05),and the fracture healing time in the research group was obviously lower than that in the control group,[(35.13±2.17)months vs(45.62±2.35)months],the difference was statistically significant(t=17.6607,P<0.05).Conclusion The application of peach blossom tang,manual reduction splint or plaster fixation therapy of closed fracture of extremities and practical effect of inflammatory cytokines in the body can promote the rapid healing,and it is conductive to reducing the inflammatory cell factor level,and it is of positive significance to ensuring the curative effect and prognosis.