摘要
目的该次研究主要针对不同病程湿性年龄相关性黄斑变性借助抗VEGF药物进行治疗的具体效果进行分析。方法该次研究按照对比治疗的模式展开,方便选取的病例按照患者病程进行分组,均为苏州吴江区第一人民医院接诊患者,其中54例(共计54只患眼),其患病时间在6月以下,即观察组,另54例(共计54只患眼),其患病时间在6~12月,即对照组。两组患者均为该院在2016年5月—2018年3月所接诊,且均借助抗VEGF治疗,针对疗效间差异加以分析。结果结合对两组患者ETDRS量表评估可知,在用药前两组差异有统计学意义(P<0.05);而在分别用药3月后,观察组视力表为(14.65±1.06)改善情况显著优势对照组(t=12.579,P<0.05);且结合对患者CRT测量可知,观察组减少量(156.56±2.07)μm同样优于对照组(t=17.078,P<0.05)。结论就湿性年龄相关性黄斑变性而言,病变时间在6月以下患者使用抗VEGF恢复更为理想,可帮助其视力得到有效改善,对于提升患者生活质量同样存在有积极意义。
Objective To analyze the specific effect of anti VEGF drugs in treatment of wet age-related macular degeneration in different stages.Methods The cases were divided into groups with54cases in each,including the observation group(54affected eyes)whose prevalence time was below6months,and the control group(54affected eyes)whose prevalence time was6-12months,and the patients were convenient selected and diagnosed in our hospital from May2016to March2018,and treated with anti-VEGF,and the difference in the curative effect was analyzed.Results The ETDRS scale evaluation showed that there was obvious difference between the two groups before medication(P<0.05);after3months of medication,the vision table in the observation group was(14.65±1.06),and the improvement condition in the observation group was obviously better than that in the control group,(t=12.579,P<0.05),and the CRT measurement showed that the decrease volume in the observation group was(156.56±2.07)μm,which was better than that in the control group(t=17.078,P<0.05).Conclusion The recovery effect of anti-VEGF of patients whose lesion time was below6months is more ideal,which can help the patients improve the vision effectively,and it is of positive significance to improving the quality of life.
作者
沈毅飞
SHEN Yi-fei(Department of Ophthalmology,Wujiang First People’s Hospital,Suzhou,Jiangsu Province,215200 China)
出处
《中外医疗》
2018年第33期94-96,共3页
China & Foreign Medical Treatment