慢性乙型肝炎代表证候代谢组学研究进展

Progress in metabolomics research on chronic hepatitis B representative syndrome

在中医辨证论治中,辨证是整个治疗过程的第一道关卡,也是最为重要的一道关卡,辨证的正确与否直接影响后期的潜方用药,故治疗疾病必须提高诊断该疾病证候的水平。随着科学发展力求中医科学化、客观化,故本文综述了国内外运用代谢组学方法对慢性乙型肝炎肝郁脾虚证及湿热蕴结证两个代表证型的生物学本质和诊断标志物的探索与研究,提出了中医证候客观化、标准化研究。

In the differentiation treatment of TCM syndrome,syndrome differentiation is the first level of the whole treatment process,and it is also the most important level.The correctness of syndrome differentiation directly affects the latent drug use,sothe diagnosis level of the disease syndrome must be improved in the treatment of diseases.With the scientific development striving for scientific and objective Chinese medicine,this paper reviews the exploration and research on the biological nature and diagnostic markers of chronic hepatitis B liver stagnation and spleen deficiency syndrome and damp heat accumulation syndrome by using metabolomics methods at home and abroad,and has proposed the objectification and standardization research of TCM syndromes.