摘要
肿瘤是人类死亡的首位病因,研制疫苗防治肿瘤是当前研究的热点领域之一。麻疹病毒的减毒株是一种新型疫苗载体,它可以表达多种肿瘤蛋白,这些肿瘤包括多形性胶质母细胞瘤、多发性骨髓瘤、前列腺癌、肾细胞癌、肝胚细胞瘤、卵巢癌、宫颈癌和乳腺癌等。
Recently,it has become highlight to control cancer,the leading cause of death,by use of vaccine.The attenuated strains of Measles virus is one new type of vaccine vector,it may express many proteins of cancers including gliobastoma multiforme,multiple myeloma,prostate cancer,renal cell carcinoma,hepatoblastoma,ovarian cancer,cervical cancer,and breast cancer.
作者
李文桂
陈雅棠
LI Wen-Gui;CHEN Ya-Tang(Institute of Infectious and Parasitic Diseases,First Affiliated Hospital,Chongqing Medical University,Chongqing 400016,China)
出处
《生物技术通讯》
CAS
2018年第6期861-865,共5页
Letters in Biotechnology
基金
国家自然科学基金(30801052
30671835
30500423
30200239)
关键词
肿瘤
麻疹病毒
疫苗
carcinoma
Measles virus
vaccine
