炎性复合指标与非小细胞肺癌预后关系的研究进展

Prognostic value of the inflammatory composite index in non-small cell lung cancer

肺癌是一种炎症相关性疾病,长期慢性肺部炎症可增加肺癌罹患风险。非小细胞肺癌(nonsmall cell lung cancer,NSCLC)为肺癌最常见类型,具有发病率高,早期确诊率低,预后差的特点。研究表明,肿瘤相关性炎症反应广泛参与肿瘤起始、增殖、侵袭及转移各阶段,与疾病预后密切相关。基于炎症标志物建立的炎性复合指标有望成为非小细胞肺癌预后评估的有效指标,对准确评估病情、识别生存风险、改善远期预后具有现实意义。

Lung cancer is a kind of inflammatory related disease and long-term chronic inflammation of lung may increase the risk of suffering from it. Non-small cell lung cancer,with the characteristics of high incidence,low early diagnosis rate and poor prognosis,is the most common type of lung cancer. Studies have shown that inflammatory response is widely involved in the initiation,proliferation,invasion and metastasis of tumor,which is closely related to the prognosis of the disease. Inflammatory composite indexes are expected to be effective indicators for the prognosis evaluation of non-small cell lung cancer. It is of practical significance to accurately assess the disease,identify the risk of survival and improve long-term prognosis.