H型高血压与腔隙性脑梗死患者血流动力学变化的相关研究

Correlation between Hemodynamic Changes in Patients with H-type Hypertension and Lacunar Infarction

目的初步探讨H型高血压与腔隙性脑梗死患者血流动力学变化的影响。方法选取2017年3月～2018年4月在亳州市人民医院就诊的腔隙性脑梗死患者90例,依据血浆同型半胱氨酸水平及是否伴有高血压,将腔隙性脑梗死患者分成H型高血压组47例和非H型高血压组43例。利用颈部血管彩超评价入组患者的颈部血流动力学状态,比较两组患者血流动力学参数的差异。结果 H型高血压组患者V_(max)[(31.23±6.75)cm/s vs (34.53±4.23)cm/s]、V_(min)[(5.24±2.01)cm/s vs (8.44±1.40)cm/s]、V_(mean)[(12.71±3.03)cm/s vs (16.81±2.17)cm/s]、Q_(mean)[(7.37±1.43)ml/s vs (8.38±1.04)ml/s]均低于非H型高血压组,差异具有统计学意义(P<0.05)。H型高血压组患者PI(2.08±0.32 vs 1.56±0.21)和RI(0.84±0.45 vs 0.75±0.21)均高于非H型高血压组,差异具有统计学意义(P<0.05)。结论 H型高血压显著降低腔隙性脑梗死患者的血流速度,H型高血压是腔隙性脑梗死患者的危险因素。

Objective To investigate the effects of hemodynamic changes in patients with H-type hypertension and lacunar infarction.Methods A total of90patients with lacunar infarction who were admitted to the People's Hospital of Bozhou city from March2017to April2018were enrolled.Patients with lacunar infarction were divided according to plasma homocysteine level and hypertension.There were47patients with H-type hypertension and43patients with non-H-type hypertension.The cervical hemodynamic status of the patients was evaluated by cervical vascular ultrasonography,and the differences in hemodynamic parameters between the two groups were compared.Results Vmax in patients with H-type hypertension[(31.23±6.75)cm/s vs(34.53±4.23)cm/s],Vmin[(5.24±2.01)cm/s vs(8.44±1.40)cm/s],Vmean[(12.71±3.03)cm/s vs(16.81±2.17)cm/s],Qmean[(7.37±1.43)ml/s vs(8.38±1.04)ml/s]were lower than non-H type hypertension group,the difference was statistically significant(P<0.05).Patients with H-type hypertension had higher PI(2.08±0.32vs1.56±0.21)and RI(0.84±0.45vs0.75±0.21)than non-H-type hypertension group,the difference was statistically significant(P<0.05).Conclusion H-type hypertension significantly reduces the blood flow velocity in patients with lacunar infarction.H-type hypertension is a risk factor for patients with lacunar infarction.