MRS在鉴别颅脑原发性肿瘤及转移瘤中的探讨

MRS in Differential Diagnosis of Primary Brain Tumor and Metastatic Tumor

目的探究颅脑原发性肿瘤与转移瘤鉴别中应用磁共振波谱的临床价值。方法回顾性分析2012年1月～2018年5月在我院接受治疗的颅脑原发性肿瘤患者32例以及颅脑转移瘤患者25例的临床资料,分别记为甲组与乙组,诊断时均行MRS检查,计算并比较两组Cho/Cr、NAA/Cr、Cho/NAA。结果经MRS诊断,甲组Cho/Cr、Cho/NAA分别为(3.12±1.02)、(3.18±1.05),乙组分别为(1.96±0.53)、(2.03±0.65),甲组高于乙组,差异有统计学意义(P<0.05),甲组NAA/Cr为(1.12±0.31),乙组为(1.47±0.37),甲组低于乙组,差异有统计学意义(P<0.05)。结论颅脑原发性肿瘤与转移瘤实质区代谢物相对浓度存在较大差异,临床中可使用MRS诊断对其进行鉴别,协助诊断,为治疗提供科学依据。

Objective To explore the clinical value of magnetic resonance spectroscopy in differentiating primary brain tumor from metastatic tumor.Methods Analysis of32cases of primary brain tumor treated in our hospital from January2012to May2018and clinical data of25patients with craniocerebral metastases was made and they were recorded as group A and group B respectively.MRS examination was performed on diagnosis,and Cho/Cr,NAA/Cr,Cho/NAA were calculated and compared between the two groups.Results The Cho/Cr,Cho/NAA of group A was(3.12±1.02),(3.18±1.05),that of group B was(1.96±0.53),(2.03±0.65),group A was higher than group B,the difference was statistically significant(P<0.05).The NAA/Cr of group A was(1.12±0.31)and group B was(1.47±0.37),respectively,group A was significantly lower than those of group B,the difference was statistically significant(P<0.05).Conclusion The relative concentrations of metabolites in the parenchymal regions of primary brain tumor and metastatic tumor are quite different.MRS diagnosis can be used to differentiate and assist in the diagnosis of primary brain tumor in order to provide scientific basis for treatment.