痰热清注射液联合青霉素治疗小儿急性化脓性扁桃体炎临床观察

Clinical Observation of Tanreqing Injection Combined with Penicillin in the Treatment of Acute Suppurative Tonsillitis

目的:探讨应用痰热清注射液联合青霉素治疗小儿急性化脓性扁桃体炎的临床疗效。方法:选取我院于2011年6月-2013年6月期间收治的74例小儿急性化脓性扁桃体炎患者作为研究对象,并按照随机数字表法将其分为两组。对照组38例患儿采用青霉素以及对症支持治疗,而试验组36例患儿在对照组治疗的基础上另加痰热清注射液静滴。治疗过程中,观察并对比分析两组患儿的临床疗效、体温恢复时间、止咳时间、咽痛消失时间、住院时间以及白细胞和扁桃体肿大的复常情况。结果:试验组患儿的临床治疗总有效率为97.22%,明显高于对照组患儿的78.95%,组间相对比差异具有显著性(P<0.05);试验组患儿的体温恢复时间、止咳时间、咽痛消失时间和住院时间分均明显少于对照组患儿,差异具有显著性(P<0.05);试验组患儿的白细胞复常率和扁桃体肿大复常率均明显少于对照组患儿,差异显著(P<0.05)。结论:痰热清注射液联合青霉素是治疗小儿急性化脓性扁桃体炎的一种有效方法,并能够改善小儿的临床症状和免疫功能,值得临床推广使用。

Objective:To investigate the clinical curative effect of Tanreqing injection combined with penicillin in the treatment of acute suppurative tonsillitis.Methods:74 cases of children with acute suppurative tonsillitis patients which treated in our hospital from June 2011 to June 2013 were selected as the study object, which were randomly divided into control group and experimental group. The control group of 38 cases with penicillin and symptomatic supportive treatment, while the experimental group of 36 cases of children on the base of the control group plus Tanreqing Injection by intravenous drip. In the course of treatment, observation and comparison of the analysis of the clinical curative effect of two groups of children, body temperature recovery time, cough, sore throat disappeared time, hospitalization time and the white blood cells, and the enlargement of the tonsils to return to normal.Results:The total efficiency of the clinical treatment of children in the experimental group was 97.22%, significantly higher than the control group, the patients were 78.95% and between groups relative ratio difference is significant (P<0.05); Children in the experimental group the body temperature recovery time, cough, pharyngodynia disappear time and hospitalization time were significantly less than the control group patients, between the two groups of comparison, the difference is significant (P < 0.05); Children in the experimental group of white blood cell recovery rate and swelling of tonsil recovery rate was 97.22% and 94.44% were significantly less than those of the control group with 81.57% and 76.31%, compared between the two groups, the difference was significant(P<0.05).Conclusion:Tanreqing injection combined with penicillin is an effective method to treat acute suppurative tonsillitis in children, and can improve children's clinical symptoms and immune function, it is worth for clinical use.