摘要
目的:比较Scheimpflug原理摄像系统Pentacam与光学相干生物测量仪IOL Master测量角膜正常的白内障患者角膜屈光力,分析两者的一致性。方法:前瞻性临床研究。选取我院2017-01/06门诊就诊的角膜正常的白内障患者41例64眼,术前分别采用IOL Master和Pentacam测量角膜屈光力,采集的数据包括:sim K、true net power、角膜中央1.0~7.0mm直径Holladay equivalent K(EKR)(Pentacam)及Km[Km=(K1+K2)/2](IOL Master)。两种仪器测量K值之间的差异采用配对样本t检验,其相关性采用Pearson相关性分析,一致性采用Bland-Altman法。结果:角膜正常的白内障患者Pentacam测量所得true net power、角膜中央1.0、2.0、3.0mm直径EKR比IOL Master测量所得Km小;角膜中央4.5、5.0、6.0、7.0mm直径EKR比IOL Master测量所得Km大,差异具有统计学意义(均P <0. 01)。Pentacam测量所得sim K、角膜中央4. 0mm直径EKR与IOL Master测量所得Km差值最小,差值均值分别为-0.03±0.252和0.04±0.244D,差异无统计学意义(t=-1.018,P=0.313; t=1.461,P=0.149);且一致性最高,95%一致性界限分别为-0.53~0.46D和-0.43~0.52D。两种仪器间所测量K值均具有较高的相关性(均r>0. 9,P<0. 01)。结论:角膜正常的白内障患者Pentacam测量所得sim K、角膜中央4.0mm直径EKR与IOL Master测量所得Km一致性最高,但使用中需结合临床意义进一步对仪器的适用范围加以判断。
AIM:To evaluate the agreement and interchangeability of a Scheimpflug camera(Pentacam)and a partial coherence interferometry keratometer(IOL Master)in eyes having preoperative assessment for routine cataract surgery.METHODS:In this prospective clinical study,41 patients(64 eyes)with normal cornea from January 2017 to June 2017 in our hospital were enrolled.Simulated K,true net power and Holladay equivalent K(EKR)measured at 1.0 to 7.0 mm corneal diameters were measured by the Pentacam system and mean keratometer(Km)was measured by the IOL Master.Paired samples t test,Pearson correlation analysis and Bland-Altman method were used for statistical analysis.RESULTS:Among patients with cataract of normal cornea,the mean Scheimpflug K for true net power and EKR at 1.0mm,2.0mm,3.0mm corneal diameters were statistically significantly less than the mean Km(IOL Master).The EKR at 4.5mm,5.0mm,6.0mm,7.0mm of corneal diameters were significantly greater than the mean Km(IOL Master)(P<0.01 for all).The difference between Sim K and EKR at 4.0mm measured by Pentacam and Km measured by IOL Master was the smallest(-0.03D±0.252D and 0.04D±0.244D,respectively;t=-1.018,P=0.313;t=1.461,P=0.149),and it had the best uniformity with 95%credible interval of-0.53D to 0.46D(sim K)and-0.43D to 0.52D(equivalent K at 4.0mm).A Pearson correlation revealed a high correlation for corneal power measurements between the two devices(r>0.9 for all,P<0.01 for all).CONCLUSION:The sim K and EKR at 4.0mm had the closest match with the Km(IOL Master)for Chinese patients with cataract of normal cornea.However,the application of these devices should be combined with clinical features.
作者
曹建雄
刘伟
刘妍
谢梅芬
张映平
常平骏
肖天林
Jian-Xiong Cao;Wei Liu;Yan Liu;Mei-Fen Xie;Ying-Ping Zhang;Ping-Jun Chang;Tian-Lin Xiao(Department of Ophthalmology,Xiangtan Central Hospital,Xiangtan 411100,Hunan Province,China;Eye Hospital,Wenzhou Medical College,Hangzhou 310000,Zhejiang Province,China;Aier Eye Hospital(Changsha),Changsha 410000,Hunan Province,China)
出处
《国际眼科杂志》
CAS
北大核心
2019年第1期113-117,共5页
International Eye Science
基金
湘潭市科技局计划项目(No.ZJ20151004).