肝素-泊洛沙姆407新材料应用进展

Application Progress of Heparin-poloxamer 407 New Compound

查阅关于肝素-泊洛沙姆407材料的国内外文献,介绍肝素-泊洛沙姆407新材料的合成及临床应用进展。从血管缝合、药物载体应用、血管修复、脊髓细胞及宫腔修复等方面介绍了肝素-泊洛沙姆407新材料的作用和特点。肝素-泊洛沙姆407是目前新兴的具有高亲和性、抗凝生物活性、缓释、定点释放等多种功能为一体的多聚物材料,既有抗凝作用可辅助血管缝合术治疗,又能在多种疾病治疗中起到良好辅助效果。

To discuss the topic of heparin-poloxamer407compound in medical progress by consulting relative literature.After that,heparin-poloxamer407compound used in vascular anastomosis、combined with growth factor for target therapy,vascular,etal spinal cord cell and uterine cavity repaired and has become a new methods according to the characteristics of it's form.Heparin-poloxamer407compound is not only a new form with the characteristics of high-affinity,anticoagulant biological activity,slow and controlled-release,but also can assist surgical operation of vessel anastomosis,and become a good assistant of some kinds of disease.