摘要
目的:分析引导性组织再生(GTR)联合植骨术治疗Ⅰ型牙周-牙髓联合病变的临床疗效。方法:纳入因牙髓及根尖周病变引起的牙周-牙髓联合病变患者28例,共38个患牙。所有患牙经完善的根管治疗及牙周基础治疗后,根据患者的意愿分为两组:实验组(n=20),翻瓣置Bio-gene骨材料并覆盖Bioguide生物膜;对照组(n=18),仅行单纯牙周翻瓣术。分别记录患者术前、术后6个月牙周探诊深度(PD)、牙龈退缩(GR)、临床附着丧失(CAL)、牙齿松动度(TM)以及牙槽骨高度(AH),并进行统计分析。结果:术后6个月,两组PD、CAL、TM、GR较术前均有显著改善(P<0.05);与对照组相比,实验组PD和CAL明显降低(P<0.05),TM和GR两组间相比则无统计学差异(P> 0.05);X线片示,实验组有15个(75.00%)患牙有新骨形成,AH增加;而对照组有1个患牙(5.56%)AH略有增加。结论:GTR联合植骨术治疗牙髓及根尖周病变引起的牙周-牙髓联合病变的临床疗效优于单纯牙周翻瓣术。
AIM:To evaluate the clinical effects of guided tissue regeneration(GTR)in combination with bone grafting in the treatment of combined periodontal-endodontic lesions.METHODS:28 patients(38 teeth with primary endodontic lesion and secondary periodontal involvement) after perfect root canal and periodontal initial therapy still with periodontal surgery indications,were divided into 2 groups according to the will of patients.20 teeth in experimental group were treated with flap and Bio-gene bone material,then covered by Bio-guide biofilm.18 teeth in control group were treated by simple flap surgery.Before and 6 months after operation periodontal probing depth(PD),gingival recession(GR),clinical attachment loss(CAL),tooth mobility(TM) and alveolar bone height(AH) were measured.The data were statistically analyzed.RESLULTS:6 months after operation,PD,CAL and TM in the 2 groups were significantly improved than those on the baseline(P<0.05),whereas GR was increased(P<0.05).Compared with control group,PD and CAL of experimental group were significantly decreased(P<0.05).No significant difference in TM and GR variation was observed between the 2 groups(P>0.05).X-ray showed there was new bone formation in 15 teeth(75%) of experimental group and AH was increased significantly compared with pre-operation.CONCLUSION:In treatment of teeth suffering from primary endodontic lesion with secondary periodontal involvement,the application of GTR combined with bone grafts may gain better clinical effects than flap surgery.
作者
张敏
周艳
宦泓
孙敬伟
李乔
梅幼敏
ZHANG Min;ZHOU Yan;HUAN Hong;SUN Jing - wei;LI Qiao;MEI You - min(Department of Periodontal Disease, Nantong Stomatology Hospital, Nantong 226001, China)
出处
《牙体牙髓牙周病学杂志》
CAS
2018年第12期720-723,共4页
Chinese Journal of Conservative Dentistry
基金
江苏省口腔疾病研究重点实验室开放课题基金(JSKLOD-KF-1703)
南通市口腔医院优秀青年医学人才培养项目基金(KY2017001)