全盆底网片悬吊术干预对盆腔脏器脱垂患者生活质量的短期影响

Short-term assessment for quality of life in patients with pelvic organ prolapse receiving total pelvic reconstruction

目的了解盆腔脏器脱垂(pelvic organ prolapse,POP)患者生活质量,评估全盆底网片悬吊手术对POP患者生活质量评分的短期干预效果。方法将接受改良全盆底网片悬吊手术的68例患者作为研究组,接受prolift手术的37例患者为对照组;分别在术前、术后1个月时采用盆底生活质量评价量表(PFIQ-7)进行调查。描述2组患者的一般情况、手术前后生活质量评分,并对2组患者手术后生活质量评分改善程度进行对比分析。结果对比研究组、对照组手术前后PFIQ-7生活质量调查表评分情况,术后生活质量评分明显改善(P<0. 05)。对2组间手术前后PFIQ-7生活质量评分改善程度(差值)进行对比:虽然2组间的总评分相比差异无统计学意义(t=0. 761,P=0. 499),但在肠道或直肠症状的评分改善程度上,prolift术优于改良全盆底网片悬吊手术(t=2. 186,P=0. 031);在阴道或盆腔症状评分改善上,改良全盆底网片悬吊手术优于prolift术(t=-6. 155,P=0. 000)。结论改良全盆底网片悬吊术和prolift手术短期均能明显改善POP患者的生活质量。在肠道或直肠症状评分改善上,prolift手术优于改良全盆底网片悬吊手术;在阴道或盆腔症状评分改善上,改良全盆底网片悬吊手术具有明显的优势。

Objective To assess the short-term improvement of the quality of life in patients with pelvic organ prolapse(POP)after surgical intervention.Methods Sixty-eight patients with POP were treated with the modified total pelvic reconstruction(study group)and37POP patients were treated with prolift procedure(control group).The PFIQ-7quality of life scores were assessed before and1month after intervention;the improvement of the quality of life was compared between two groups.Results There were significant differences in PFIQ-7scores before and after intervention in both two groups(P<0.05).The improvement of the intestinal or rectal symptoms were more marked in control group than that in study group(t=2.186,P=0.031);while the improvement of vaginal or pelvic symptoms was more marked in study group than that in control group(t=-6.155,P=0.000).No significant difference was found between the two groups in the overall PFIQ-7scores after operation(t=0.761,P=0.449).Conclusion Short-term assessment shows that both the modified total pelvic reconstruction and the prolift surgical operation can significantly improve the quality of life in POP patients with their own advantages.