阿托伐他汀、辅酶Q_(10)联合应用治疗冠心病早期心功能减退的应用价值

Atorvastatin combined with coenzyme Q10 in the treatment of early cardiac dysfunction in patients with coronary heart disease

目的:探讨冠心病早期心功能减退治疗中阿托伐他汀联合辅酶Q_(10)的应用价值。方法:收治冠心病早期心功能减退患者68例,随机分观察组(34例,阿托伐他汀)和对照组(34例,阿托伐他汀、辅酶Q_(10)联合)。结果:观察组在左室射血分数(LVEF)、左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD)以及不良反应发生率指标上,比对照组改善更明显(P<0.05)。结论:辅酶Q_(10)于冠心病早期心功能减退患者常规治疗的基础上应用,可有效促进其各项心功能指标的改善与恢复,实现临床疗效的提升,同时,具有较好的用药安全性。

Objective:To explore the value of atorvastatin combined with coenzyme Q10in the treatment of coronary heart disease with early cardiac dysfunction.Methods:68patients with early coronary heart disease were randomly divided into the observation group(34cases,atorvastatin)and the control group(34cases,atorvastatin combined with coenzyme Q10).Results:The improvement of left ventricular ejection fraction(LVEF),left ventricular end systolic diameter(LVESD),left ventricular end diastolic diameter(LVEDD)and the incidence of adverse reactions in the observation group were more obvious than that in the control group(P<0.05).Conclusion:CoQ10can effectively promote the improvement and recovery of cardiac function indexes and improve the clinical efficacy in patients with early coronary heart disease on the basis of routine treatment,at the same time,it has better medication safety.