阿奇霉素联合孟鲁司特钠对肺炎支原体肺炎患儿血清CRP水平的影响

Effect of azithromycin combined with montelukast sodium on serum CRP level in children with mycoplasma pneumoniae pneumonia

目的:探讨阿奇霉素联合孟鲁司特钠对肺炎支原体肺炎患儿血清CRP水平的影响。方法:收治肺炎支原体肺炎患儿106例,随机分成对照组与观察组。对照组采用阿奇霉素序贯疗法治疗,观察组采用阿奇霉素序贯疗法联合孟鲁司特钠治疗,比较两组临床总有效率、治疗前后CRP水平变化。结果:观察组治疗总有效率明显高于对照组(P<0.05);观察组血清CRP水平显著低于对照组(P<0.05)。结论:阿奇霉素联合孟鲁司特钠治疗肺炎支原体肺炎患儿的疗效优于单独应用阿奇霉素,并且能显著降低患儿血清CRP水平。

Objective:To explore the effect of azithromycin combined with montelukast sodium on serum CRP level in children with mycoplasma pneumoniae pneumonia.Methods:106children with mycoplasma pneumoniae pneumonia were selected,they were randomly divided into the control group and the observation group.The control group was treated with azithromycin sequential therapy,the observation group was treated with azithromycin sequential therapy combined with montelukast sodium,we compared the clinical total effective rate,CRP level changes before and after treatment of two groups.Results:The total effective rate of the observation group was significantly higher than that of the control group(P<0.05).The serum CRP level in the observation group was significantly lower than that in the control group(P<0.05).Conclusion:The curative effect of of azithromycin combined with montelukast sodium in the treatment of children with mycoplasma pneumoniae pneumonia was better than azithromycin alone,and it can significantly reduce the serum CRP level of children.