去甲肾上腺素低压保留灌肠治疗方案对内镜下肠息肉切除术后患者的临床应用分析

Analysis on clinical application of norepinephrine low pressure enema treatment scheme in patients with endoscopic intestinal polypectomy

目的分析内镜下肠息肉切除术后应用去甲肾上腺素低压保留灌肠治疗方案的效果。方法选取2016年1月～2017年12月于我院行内镜下肠息肉切除术患者120例,按照随机数字表法分为观察组和对照组,各组60例。两组患者均接受对症基础治疗,对照组患者应用静脉止血剂治疗;观察组在对照组的基础上给予去甲肾上腺素低压保留灌肠治疗。观察两组肠道出血及不良反应情况。结果观察组患者2d内出血得到控制,而对照组患者多数在2d以后出血受控制,两组出血控制时间分布对比,差异有统计学意义(P <0.01);观察组出血控制平均时间[(32.84±4.85)h]较对照组[(45.68±6.52)h]短,差异有统计学意义(P <0.001);观察组患者4d内出血痊愈,而对照组多数患者4d内出血痊愈,少部分4d后痊愈,两组出血痊愈时间分布对比,差异有统计学意义(P <0.01);观察组出血痊愈平均时间[(47.35±8.42)h]较对照组[(69.43±12.56)h]短,差异有统计学意义(P<0.001);两组治疗过程中无不良反应,且创面愈合良好。结论去甲肾上腺素低压保留灌肠治疗方案能有效的缩短内镜下肠息肉切除术后出血时间和出血愈合时间,有利于患者的康复。

Objective To analyze the effect of norepinephrine low pressure retention enema treatment scheme after endoscopic intestinal polypectomy.Methods 120 patients who underwent endoscopic intestinal polypectomy in our hospital from January 2016 to December 2017 were selected.They were divided into observation group and control group according to random number method,with 60 cases in each group.Patients in two groups were all given symptomatic basic treatment.Patients in the control group were treated with intravenous hemostatic agents while patients in the observation group were treated with norepinephrine low pressure retention enema on basis of the control group.Intestinal bleeding and adverse reactions of two groups were observed.Results The bleeding in the observation group was controlled within 2 days while that of the majority in the control group was controlled after 2 days.The time distribution of bleeding control was statistically significant(P<0.01).The mean time of bleeding control in the observation group was(32.84±4.85)h,shorter than that in the control group(45.68±6.52)h,and the difference was statistically significant(P<0.001).The patients in the observation group recovered within 4 days while the majority of the patients in the control group recovered within 4 days and a small number of patients recovered after 4 days.The distribution of bleeding healing time in the two groups was statistically significant(P<0.01).The mean recovery time of bleeding in the observation group(47.35±8.42)h was shorter than that in the control group(69.43±12.56)h,and the difference was statistically significant(P<0.001).There were no adverse reactions during the treatment in the two groups,and the wounds healed well.Conclusion Norepinephrine low pressure retention enema treatment scheme can effectively shorten bleeding time and bleeding healing time after endoscopic intestinal polypectomy,which is beneficial to the rehabilitation of patients.