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心肌致密化不全合并肾脏疾病14例临床分析 被引量:1

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摘要 目的探讨心肌致密化不全合并肾脏疾病的临床特点。方法收集我院住院病历资料完整的心肌致密化不全病人48例,根据是否合并肾脏疾病分组。对照组34例,合并肾脏疾病组14例,回顾性分析各组病人的临床表现、超声心动图资料以及实验室检测资料等。结果对照组34例,否认肾脏疾病合并史。肾脏疾病组为14例,其中慢性肾脏病(CKD)3-4期4例(28.6%),CKD5期5例(35.7%),急性肾损伤2例(14.3%),多囊肾3例(21.4%)。两组的血肌酐(Scr)、血尿素氮(BUN)、血红蛋白(Hb)、血钙、血磷、甲状旁腺激素(iPTH)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)及C-反应蛋白(CRP)等比较具有统计学意义。临床观察对照组心力衰竭67.6%,而合并肾脏疾病组病人均有心力衰竭;对照组血栓栓塞为5.9%,肾脏疾病组病人无血栓栓塞病例;对照组心律失常58.8%,肾脏疾病组78.6%。采用超声心动图观察,与对照组比较,除室间隔厚度及E/A外,合并肾脏疾病组病人的左室舒张末内径、左室后壁厚度、左房前后径及左室射血分数均有统计学意义。结论心肌致密化不全合并肾脏疾病病人临床表现相对严重,预后相对较差,其发病机制可能与多种病因参与有关。
出处 《中西医结合心脑血管病杂志》 2018年第23期3563-3565,共3页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
基金 山西省科技攻关项目(No.20130313018-4)
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