优化方案对复治肺结核合并糖尿病的疗效

Efficacy of Optimized Regimens in Recurrent Pulmonary Tuberculosis Patients With Diabetes Mellitus

目的研究规范化方案和优化方案在复治肺结核合并糖尿病患者中的应用效果。方法临床纳入2016年2月—2017年2月我院收治的78例复治肺结核合并糖尿病患者作为研究对象,按随机数字表法分为两组各39例。其中39例患者采用优化方案治疗作为优化组;另39例患者采用规范化方案治疗作为规划组。观察两组患者治疗效果及不良反应情况。结果优化组治疗总有效率为94.87%,高于规划组的79.49%,P <0.05。优化组不良反应发生率为2.56%,低于规划组的17.95%,P <0.05。结论在复治肺结核合并糖尿病患者中采用优化治疗方案治疗效果较好,不良反应少,患者术后恢复更佳。

Objective To study the application value of optimized regimens and standardized regimens in recurrent pulmonary tuberculosis patients with diabetes mellitus.Methods 78 recurrent pulmonary tuberculosis patients with diabetes mellitus treated February 2016 to February 2017 in our hospital were selected and randomly assigned to optimized group and standardized group,39 cases in each group.Patients took the optimized regimens or standardized regimens,respectively.The therapeutic effect and adverse reactions were estimated.Results The total effective rate in the optimized group(94.87%)was significantly higher than standardized group(79.49%)(P<0.05);the adverse event rate in the optimized group(7.69%)was significantly lower than standardized group(17.95%)(P<0.05).Conclusion The optimized regimens can increase the therapeutic effect,reduce the adverse event rate and promote the patient’s postoperative recovery.