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宁波地区高危型HPV E6/E7mRNA阳性患者的临床病理特点分析 被引量:2

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摘要 目的探讨宁波地区高危型HPV E6/E7m RNA阳性患者的临床病理特点。方法收集高危型HPV E6/E7m RNA检测病例2 495例,其中检测结果为阳性571例。采用专用的宫颈刷采集患者的宫颈脱落细胞,利用杂交捕获法检测高危型HPV E6/E7m RNA,并进一步分型为16型、18/45型和其他11型,检测结果由软件自动判读为阳性、阴性和无效结果。回顾性分析阳性患者的临床病理特点,包括高危型HPV E6/E7m RNA的型别、液基细胞检查结果、组织病理结果及年龄构成等。结果高危型HPVE6/E7m RNA阳性患者在TCT检查为NILM的比率远远高于TCT检查结果异常者;挖空、湿疣及LSIL占比达59.34%;高危型HPV阳性与阴性患者不同年龄组构成比差异有统计学意义(P <0.05)。结论宁波地区高危型HPV E6/E7m RNA阳性患者的年龄以30~55岁为高发,类型以其他11型常见,组织病理结果显示湿疣及挖空最多。
出处 《现代实用医学》 2018年第12期1648-1650,共3页 Modern Practical Medicine
基金 宁波市医学科技计划项目(2016A55)
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