摘要
在微波辅助作用下,以3种咪唑类离子液体水溶液为提取溶剂,研究了红花药材中提取总黄酮的工艺的单因素条件,并与药典提取方法进行了比较。研究结果表明:3种离子液体水溶液作为提取溶剂可以有效提取红花中的总黄酮,特别是离子液体溴化1-辛基-3-甲基咪唑盐([C_8mim]Br)的水溶液,以料液比1∶40,设置微波功率400 W,微波时间15 min,微波温度80℃时,提取出的黄酮含量最高,提取率可达3.24%;与药典提取方法相比,提取时间由3 h缩短到15 min,提取率提高了0.65%。
With assistance of microwave,the single factors for extracting total flavonoids from safflower were studied by using the aqueous solution of three imidazolium ionic liquids as extraction solvent.Further comparison with pharmacopoeia extraction method was also carried out.The results showed that the aqueous solution of the three imidazolium ionic liquids can be used to effectively extract the total flavonoids from safflower,especially the aqueous solution of 1-octyl-3-methyl bromide imidazole salt([C8mim]Br).With the conditions of solid-liquid ratio1∶40,microwave power400w,microwave time15min and microwave temperature80℃,the highest extraction yield of 3.24% for total flavonoids was obtained.Compared with the pharmacopoeia extraction method,the extraction time was shortened from3h to15min,and the extraction rate was improved by0.65%.
作者
王鑫
孟丹
葛秀娟
赵三虎
WANG Xin;MENG Dan;GE Xiujuan;ZHAO Sanhu(Department of Chemistry,Xinzhou Teachers University,Xinzhou 034000,China;School of Chemistry and Material Science,Shanxi Normal University,Linfen 041001,China)
出处
《海南师范大学学报（自然科学版）》
CAS
2018年第4期377-382,共6页
Journal of Hainan Normal University（Natural Science）
基金
山西省自然科学基金(201601D102015)
忻州师范学院大学生创新创业项目([2016]32)
关键词
红花
黄酮
提取
离子液体
safflower
flavonoids
extraction
ionic liquid
