期刊文献+

生长激素缺乏症对心血管系统病变的影响分析 被引量:4

Effect of Growth Hormone Deficiency on Cardiovascular System Lesions
下载PDF
导出
摘要 目的:探讨机体的生长素缺乏症对心血管系统的影响。方法:将60例患有生长素缺乏症的患者分为两组,生长素缺乏症治疗组为A组,生长素缺乏症未治疗组为B组,比较两组心血管疾病的发生率。结果:A组心血管疾病的发生率明显低于B组(P<0.05),有统计学意义。结论:生长激素缺乏症会增加心血管疾病的发病率、死亡率,导致机体心脏结构及功能损害、脂质代谢异常,内皮细胞功能紊乱,危害机体健康。 Objective:This article mainly discusses the effects of growth hormone deficiency on the cardiovascular system.Methods:60 patients with auxin deficiency were divided into group A with auxin deficiency treatment group and group B without auxin deficiency treatment.The incidence of cardiovascular disease was compared between the two groups.Results:The incidence of cardiovascular disease in group A was significantly lower than that in group B(P<0.05),with statistical significance.Conclusion:Growth hormone deficiency can increase the incidence of cardiovascular disease and mortality,lead to structural damage and dysfunction of the heart,abnormal lipid metabolism,dysfunction of endothelial cells,and endanger the health of the body.
作者 张艳芳 韩雪 Zhang Yanfang(Department of Emergency,Kaifeng Children's Hospital,Kaifeng 475100)
出处 《数理医药学杂志》 2019年第1期56-57,共2页 Journal of Mathematical Medicine
关键词 生长激素缺乏症 心血管系统 病变 growth hormone deficiency cardiovascular system lesions
  • 相关文献

参考文献6

二级参考文献128

  • 1Molitch ME, Clemmons DR, Malozowski S, et al. Evaluation and treatment of adult growth hormone deficiency : an Endocrine Society Clinical Practice Guideline[ J]. J Clin Endocrinol Metab,2006,91 (5) :1621 -1634.
  • 2Ho KK. Consensus guidelines for the diagnosis and treatment of a- dults with GH deficiency II :a statement of the GH Research Soci- ety in association with the European Society for Pediatric Endocri- nology, Lawson Wilkins Society, European Society of Endocrinolo- gy,Japan Endocrine Society, and Endocrine Society of Australia [ J ]. Eur J Endocrinol,2007,157 ( 6 ) :695 - 700.
  • 3Cook DM, Yuen KC, Biller BM, et al. American Association of Clinical Endocrinologists medical guidelines for clinical practice for growth hormone use in growth hormone-deficient adults and transition patients - 2009 update [ J ]. Endocr Pract, 2009, 15 (Sappl 2) :1 -29.
  • 4Stochhohn K, Gravholt CH,Laursen T,et al. Mortality and GH de- ficiency : a nationwide study [ J ]. Eur J Endocrinol,2007,157 ( 1 ) : 9-18.
  • 5Yuen KC, Biller BM, Molitch ME, et al. Clinical review : Is lack of recombinant growth hormone (GH) -releasing hormone in the Unit- ed States a setback or time to consider glucagon testing tor adult GH deficiency? [ J ]. J Clin Endocrinol Metab, 2009, 94 ( 8 ) : 2702 - 2707.
  • 6Giavoli C, Libe R, Corbetta S, et al. Effect of recombinant human growth hormone(GH) replacement on the hypothalamic-pituitary- adrenal axis in adult GH-deficient patients [ J ]. J Clin Endoerinol Metab,2004,89 ( 11 ) :5397 - 5401.
  • 7Porretti S,Giavoli C,Ronchi C,et al. Recombinant human GH re- placement therapy and thyruid function in a large group of adult GH-deficient patients:when does L-T(4) therapy become manda- tory ? [ J ]. J Clin Endocrinol Metab,2002,87 (5) :2042 - 2045.
  • 8Clemmons DR. The relative roles of growth hormone and IGF-1 in controlling insulin sensitivity [ J ]. J Clin Invest, 2004, 113 ( 1 ) : 25 - 27.
  • 9Svensson J and Bengtsson BA. Safety aspects of GH replacement [ J ]. Eur J Endocrinol,2009,161 ( Suppl 1 ) S65 - 74.
  • 10Maison P,Griffin S,Nicoue-Beglah M,et al.Impact of growth hormone(GH)treatment on cardiovascular risk factors in GH-deficient adults:a Meta analysis of Blinded,Randomized,Placebo-Controlled Trials[J].J Clin Endocrinol Metab,2004;89:2192-9.

共引文献22

同被引文献34

引证文献4

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部